加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

Fascin/FSCN1抗体图片
产品货号:
Z16755
中文名称:
Fascin/FSCN1抗体
英文名称:
Anti-Fascin/FSCN1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Fascin/FSCN1 Antibody
指标别名55kDa actin bundling protein;FAN1;Fascin;Fascin 1;Fascin;FSCN1;HSN;p55;Singed like protein;SNL
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称FSCN1
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the N-terminus of human Fascin(97-113aa DDGRWSLQSEAHRRYFG),identical to the related rat and mouse sequences.
计算分子量55KD
实际分子量55KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Fascin is a actin cross-linking protein.The Fascin gene contains 5 exons and spans 7kb.It is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates,including humans.Fascin(from the Latin for bundle) is spaced at 11 nanometre intervals along the filament.The bundles in cross section are seen to be hexagonally packed,and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins.It is calcium insensitive and monomeric.Fascin binds beta-catenin,and colocalizes with it at the leading edges and borders of epithelial and endothelial cells.The role of Fascin in regulating cytoskeletal structures for the maintenance of cell adhesion,coordinating motility and invasion through interactions with signalling pathways is an active area of research especially from the cancer biology perspective.Abnormal fascin expression or function has been implicated in breast cancer,colon cancer,esophageal squamous cell carcinoma,gallbladder cancer and prostate cancer.
Uniprot IDQ16658
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称fascin homolog 1,actin-bundling protein(Strongylocentrotus purpuratus)
蛋白名全称Fascin
推荐稀释比
Western blot (WB) 1:500~2000

相关搜索:Fascin/FSCN1抗体Fascin抗体FSCN1多抗Anti-Fascin/FSCN1 Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3